Mesenchymal Stromal Cells: Facilitators of Successful Transplantation?
نویسندگان
چکیده
منابع مشابه
Mesenchymal stromal cells to promote solid organ transplantation tolerance.
PURPOSE OF REVIEW Mesenchymal stromal cells (MSCs) possess unique immunomodulatory features. MSCs dampen effector T-cell response while promoting the emergence of regulatory T cells. By skewing this balance, MSC could represent the ideal strategy for tolerance induction in organ transplantation. Here we review recent evidence on the efficacy of MSC-based therapy in experimental models of solid ...
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ژورنال
عنوان ژورنال: Cell Stem Cell
سال: 2010
ISSN: 1934-5909
DOI: 10.1016/j.stem.2010.09.009